National Headlines

A woman with advanced ovarian cancer has become the first patient in the world to receive a pioneering new therapy, in what is being hailed as a "landmark moment".

Labour grandee Harriet Harman has said Labour should ban men from running in its next leadership election.

A renowned climber who served in the British special forces is missing after an avalanche on one of the world's highest mountains.

BP has placed its North Sea oil and gas business up for sale.

Sainsbury's has revealed it is selling Argos under a "business as usual" deal that will allow the company to concentrate on its core grocery business.

One of Britain's biggest high street bookmakers is to axe hundreds of jobs as it prepares to close more than 130 shops amid a deepening tax raid on the industry.

British YouTuber and rapper Yung Filly has been found not guilty of raping a woman in an Australian hotel room almost two years ago.

Gianni Infantino is rapidly losing support to remain as FIFA president, Sky News has learned, after European nations announced a World Cup boycott if he goes ahead with selling part of the tournament to private investors.

A Virgin Atlantic engineer died of a traumatic brain injury after an explosion as he worked inside a plane fuel tank, an inquest heard.

Two of the High Speed 2 (HS2) railway's most significant private sector deals have been renegotiated, the government will announce on Friday, as it tries to demonstrate that Britain's biggest infrastructure white elephant is finally under control.